Plummer-Vinson 증후군 = A Case of Plummer-Vinson Syndrome

다국어 초록 (Multilingual Abstract)

Background: Plummer-Vinson Syndrome is a rare disease in middle-aged women with symptomatic hypopharyngeal webs, iron deficiency anemia, oral-hypopharyngeal mucosal lesions. A 30-year-old woman was admitted to the hospital because of dysphagia, inappropriate mastication, and dizziness. Three months ago above symptoms were aggravated, and she was transferred to our hospital under the impression of esophageal obstruction. On the admission, she was chronic ill-looking appearance with pale conjunctivae, poor oral hygiene, tongue atrophy. So we studied the patient under the impression of Plummer-Vinson Syndrome. Method: Work-up included CBC, PBS, serum iron and TIBC, esophagography, bone marrow studies, and esophagoscopy. Results: The peripheral blood exam. showed microcytic and hypochromic anemia with serum iron & TIBC of 53 ㎍/㎗ & 520 ㎍/㎗. Bone marrow study revealed markedly decreased iron stain. The esophagography and esophagoscopy showed web-like mucosal lesion on anterior wall of the upper esophagus. On the 11th hospital day, endoscopic dilatation with a bougie and iron supplementation were done with clinical improvement of dysphagia and abdominal pain. Six months after discharge, there was a gradual improvement in anemia, follow-up esophagography showed markedly dilatated upper esophagus than pre-dilatated state. Conclusion: We experienced a 30-year-old female with the chief complaints of dysphagia and oral mucosal lesion. After evaluation, we found a upper esophageal web and iron deficiency anemia and treated with endoscopic dilatation and iron supplementation. So we report Plummer-Vinson syndrome with the review of relevant literature.