Neutron Dose Response of Tradescantia Stamen Hair Pink Mutations and RBE = 자주달개비 수술털 분홍돌연변이의 중성자 선량반응과 RBE

국문 초록 (Abstract)

자주달개비 4430 클론에 있어서 252Cf 중성자에 의해 유발되는 유전자 돌연변이의 선량반응 관계를 확립함과 동시에 TSH 분홍돌연변이를 유발함에 있어서 X-선에 대비한 중성자의 생물학적 효과비를 산출하였다. 돌연변이를 분석은 공시재료의 방사선조사후 4주 이상 이뤄졌으며 최대변이율을 보이는 조사후 6일부터 13일 까지의 분석결과로 부터 돌연변이빈도를 산출하였다. 가용한 실험범위내에서 중성자 선량의 증가에 따라 돌연변이빈도의 성형적 증가 양상을 나타내었다. X-선에 비교하여 산출한 중성자의 RBE값에 비해 상당히 낮은 값이다.

다국어 초록 (Multilingual Abstract)

Dose response relationships for one of biological end-points(gene mutation) in somatic cells of Tradescantia 4430 clones were studied using neutrons coming out of a californium-252 isotopic source. And the relative biological effectiveness (RBE) of neutrons in relation to X-ray in the induction of TSH pink mutaions was assessed. Inflorescences were irradiated with X-ray from X-ray generator and neutrons from 252Cf source. Irradiated cuttings were incubated with aeration in neutrient solution under the controlled condition. For more than 4 weeks after irradiation cell mutations were scored. Pink mutation frequencies were calculated from the pooled data for the peak interval (days 6 to 13 post-irradiation). Somatic cell mutations in TSH showed linear dose response relationships in the range of neutron doses available for the experiment. The RBE values estimated for neutrons in relation to X-rays were in the range 3.1 to 6.8 which were much lower than normally recognized value.