補虛湯이 免疫機能에 미치는 影響 = The immunoadjuvant effects of BoheuTang

다국어 초록 (Multilingual Abstract)

For the purpose of investigate the immunoadjuvant effects of BoheuTang, BoheuTang was pretreated to Balb/c mice for 10 days with intraperitoneally. After 10 days, haptenic antigen (VCR-BSA, vincristine-bovine serum albumin) complexed with Freund's complete adjuvant was immunized. The immunoadjuvant were followed after 7 days of first immunization. The immunoadjuvant experimentswere as follows :
1. The antibody production in Balb/c mouse immunized with VCR-BSA was remarkably increased in the pretreated group of BoheuTang compared with saline treated(control) group.
2. The macrophage numbers in Balb/c mouse immunized with VCR-BSA was considerably increased about 2.9 times in the pretreated groups of BoheuTang compared with control group.
3. The lysozyme activity of macrophage in Balb/c mouse that was immunized with VCR-BSA was increased gradually in the pretreated groups of BoheuTang compared with control group.
4. In the BoheuTang pretreated group, B cell(spleen cell) proliferation was increased with a dose dependent manner. At 20μl/well of BoheuTang, B cell proliferation activity was most highest.
5. Onthe other hand, in the T cell(thymocyte) proliferation BoheuTang pretreated group had less considerable activity than in the case of B cell.
These results may suggest that BoheuTang will have immunoadjuvant effects on the cells which concerned with immuno mechanism.

목차 (Table of Contents)

• Ⅰ. 緖論
• Ⅱ. 材料 및 方法
• Ⅲ. 實驗結果
• Ⅳ. 考察
• Ⅴ. 結論
• 參考文獻
• Abstract