正常 및 Reserpine 前處置 家兎의 摘出臟器에 對한 Catecholamines의 效果에미치는 Calcium의 影響 = Influence of Ca concentration on responses of isolated organs of normal and reserpinized rabbits to catecholamines

다국어 초록 (Multilingual Abstract)

Dahlia et al. reported that increasing the concentration of Ca in the bathing medium from 0.625 mM to 2.5 mM decreased response of rat ventricle to norepinephrine, but Sullivan et al. showed that variation of Ca concentration between 0.15 mM and 2.4 mM had no significant effect on response of rabbit aortic strips to norepinephrine.
In order to investigate the influence of Ca concentration on responses of the isolated organs of norma and reserpinized rabbits to catecholamines, author observed the contractile responses of the isolated atria, aortic strips, splenic capsules and vas deferenses of normal and reserpinized rabbits to epinephrine and norepinephrine in Locke-Ringer bathing medium containing 1.2 mM and 2.4 mM Ca respectively.
The results obtained were summarized as follows:
1. In 1.2 mM Ca Locke-Ringer medium than normal Locke-Ringer medium (containing 2.4 mM Ca). responses of isolated atria and aortic strips of normal rabbits to both epinephrine and norepinephrine were more significantly increased, and responses of vas deferenses not significantly increased, but responses of splenic capsules rather decreased.
2. In normal Locke-Ringer medium, responses of isolated atria, aortic strips and vas deferenses to both catecholamines were significantly increased by reserpine pretreatment, but by decrease of calcium concentration in Locke-Ringer medium to 1.2 mM, the increase of the responses by reserpine pretreatment were not affected.

목차 (Table of Contents)

• Ⅰ. 緖論
• Ⅱ. 實驗材料 및 方法
• 1. 摘出心房에 對한 實驗
• 2. 摘出大動脈片에 對한 實驗
• 3. 摘出脾臟被膜에 對한 實驗
• 4. 摘出輸精管에 對한 實驗
• Ⅲ. 實驗成績
• Ⅳ. 考察
• Ⅴ. 結論
• 參考文獻