만성활동간염의 HBsAg 양성율과 임상적 고찰 = HBsAg Positivity and Clinical Studies of Chronic Active Hepatitis만성활동간염의 HBsAg 양성율과 임상적 고찰

다국어 초록 (Multilingual Abstract)

HBsAg positivity and clinical studies in 49 cases with chronic active hepatitis, were carried out at Busan National University Hospital, from March 1978 to November 1981 The results were as follows: 1) Incidence of HBsAg was 67. 3% in cases with chronic active hepatitis. Sex distribution was 30 cases in male among HBsAg positive group and 19 cases in male among negative group. Mean age of HBsAg positive group was 35% years and negative group 43. 9 years, and there was a significant difference in mean age between both groups. 2) There was a history of acute hepatitis in 34 cases(69.4%), The interval between the acute attack and the diagnosis of chronic active hepatitis averaged 21.7 months. 3) In chemical liver function tests, SGPT and TTT were significantly increased in HBsAg positive group as compared with negative group, while SGOT, alkaline phosphatase and serum bilirubin showed no significant differences between both groups. 4) Immunoglobulin G and A were slightly increased in HBsAg negative group as compared with positive group, but there were no significant differences between both groups. 5) Jn 23 cases(13 cases with HBsAg positive and 10 cases with negative) who had been folloived for average of 20 months, incidences of improved, stabilized and aggravated cases showed no significant differences between HBsAg positive and negative group. But incidence of relapsed cases was significantly higher in HBsAg positive group than negative group.