Capabilities of the Monte Carlo Simulation Codes for Modeling of a Small Animal SPECT Camera

다국어 초록 (Multilingual Abstract)

Purpose This study aims to compare Monte Carlo-based codes’ characteristics in the determination of the basic parameters of ahigh-resolution single photon emission computed tomography (HiReSPECT) scanner.
Methods The geometry of this dual-head gamma camera equipped with a pixelated CsI(Na) scintillator and lead hexagonal holecollimator were accurately described in the GEANT4 Application for the Tomographic Emission (GATE), Monte Carlo N-particleextended (MCNP-X), and simulation of imaging nuclear detectors (SIMIND) codes.We implemented simulation procedures similarto the experimental test for calculation of the energy spectra, spatial resolution, and sensitivity of HiReSPECT by using 99mTc sources.
Results The energy resolutions simulated by SIMIND, MCNP-X, and GATE were 17.53, 19.24, and 18.26%, respectively, whileit was calculated at 19.15% in experimental test. The average spatial resolutions of the HiReSPECT camera at 2.5 cm from thecollimator surface simulated by SIMIND, MCNP-X, and GATE were 3.18, 2.9, and 2.62 mm, respectively, while this parameterwas reported at 2.82 mm in the experiment test. The sensitivities simulated by SIMIND, MCNP-X, and GATE were 1.44, 1.27,and 1.38 cps/μCi, respectively, on the collimator surface.
Conclusions Comparison between simulation and experimental results showed that among these MC codes, GATE enabled toaccurately model realistic SPECT system and electromagnetic physical processes, but it required more time and hardwarefacilities to run simulations. SIMIND was the most flexible and user-friendly code to simulate a SPECT camera, but it hadlimitations in defining the non-conventional imaging device. The most important characteristics like time and speed of simulation,preciseness of results, and user-friendliness should be considered during simulations.

참고문헌 (Reference)

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