흰쥐 절치의 치조골에서 고분자로 3D Printing한 치근형 매식체의 골유착능 평가

다국어 초록 (Multilingual Abstract)

The aim of this investigation was radiographic and histologic evaluations of the 3D reconstructed root analogue implant(RAI) placed in extraction sockets of maxillary incisor of Sprague-Dawley(SD) rats. Thirteen male 10-week-old SD rats were used in this study. Using a Micro computed tomography(μCT) scan, maxillary incisor images of the SD rat were obtained. CT images of the incisor were converted to the STL(standard triangulation language) format and RAIs were 3D-printed. The replicas were made of ABS(acrylonitrile butadiene styrene) and PLA(polylactic acid). Each replica was coated with titanium for the protection barrier. Surface morphology and thickness of coating were analyzed by the SEM(scanning electron microscope). Incisor replicas were placed into extraction sockets after a tooth extraction. After 4 weeks, rats were sacrificed and radiographic images were taken. Decalcified sections were prepared for a light microscopic study. Incisor replicas fitted into the extraction socket due to its congruence with the socket. Rats were well fed for 4 weeks without the inflammation. Radiographic images did not show any particular evidence of the bone resorption. The histometric evaluation on RAIs of ABS, PLA showed a mean mineralized bone-to-implant contact of 45.3±14.2% and 37.2±5.5%, respectively. The present data suggests that titanium coating enables osseointegration and makes polymer material possible as an dental implant.

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