화장품에 의한 접촉피부염 환자에서의 첩포시험 결과에 대한 고찰 = Review of the Patch Test Results in patients with the Cosmetic Contact Dermatitis화장품에 의한 접촉피부염 환자에서의 첩포시험 결과에 대한 고찰

다국어 초록 (Multilingual Abstract)

Background:Contact dermatitis is frequently caused by cosmetics. Detection of causative allergens is important in prevention and treatment of cosmetic contact dermatitis. Patch test has been accepted as the only reliable diagnostic method to detect allergens. Objective:The objectives of this study were to clarify evoluting trends of positive patch tests and to compare the positive frequencies of various allergens between different time sequences. Materials and methods:We reviewed patch test results of the 806 cosmetic contact dermatitis patients, who had visited our clinic from 1982 to 1997. We divided the patients into three groups as follows;Ⅰgroup:1982-1987, Ⅱ group:1988-1992, Ⅲ group :1993-1997 and compared the test results. The patch tests were performed with standard batteries, cosmetic-related allergens and the patients’s own cosmetics. Results:The results of the studies were summarized as follows; 1. Trends of increasing positivity in cosmetic-induced dermatitis was noted in a chronologic point of view. Among the patients, an increased proportion of males was notable. 2. In age distribution, a decreasing proportion of patients at the third & the fourth decades was observed. Contrary to this, the proportion of patients over the fifth decades was increased. 3. Among standard allergens, nickel sulphate showed the highest positive rate in all defined triple periods, whereas positive rates of neomycin sulphate & balsam the highest positive rate in all defined triple periods, whereas positive rates of meomycin sulphate & balsam of Peru were diminishing sequentially. Among fragrance allergens, cinnamic alcohol & cinnamic aldehyde revealed the highest positive rates. 4. In as is test, skin care products showed the highest positive rate, followed by toiletries and makeup products. Increasing positive rates of the toiletry products were observed in order of time. In fragrance products, positive rates reached their peak in the second period and declined in the third period. Conclusion:This study showed that perfume components were the most frequent allergens in cosmetics followed by preservative agents. Our study showed that cosmetic allergies in men seems to have increased.(Korean J Dermatol 1999;37(8):1009~1016)