Tuberculosis and gastrectomy : A Nationwide Population-based Matched Cohort Study = Tuberculosis and gastrectomy : A Nationwide Population-based Matched Cohort Study

다국어 초록 (Multilingual Abstract)

The objective of this study was to examine the incidence and risk of tuberculosis in patients who underwent gastrectomy. This population-based matched cohort study was conducted to analyze the sample database of the National Health Insurance Coporation. There were 2223 subjects with having gasgtrectomy as the gastrectomy group between 2008 and 2012, and 8892 randomly selected subjects without gastrectomy as the non-gastrectomy group. Subjects with history of pulmonary tuberculosis or gastric cancer before the index date 1year were excluded. Both gastrectomy and non-gastrectomy groups were matched with sex, age, Diabetes, end stage renal disease, transplantation, Chronic obstructive pulmonary disease and pneumoconiosis. The incidence of tuberculosis was assessed in both groups. The multivariable Cox proportional hazards regression model was used to assess the hazard ratio and 95% confidence interval for risk of tuberculosis associated with gastrectomy. The overall incidence of tuberculosis was 1.11-fold greater in the gastrectomy group than that in the non-gastrectomy group. After adjusting for confounding factors, the adjusted hazard ratio of tuberculosis was 1.1 for the gastrectomy group, compared with the non-gastrectomy group, but it was not significant. Old age, chronic obstructive pulmonary disease, low economic status were other factors that could be related to pulmonary tuberculosis. Further study using census data will be required.