제왕절개술후 통증조절을 위해 경막외 PCA 를 이용한 Meperidine 단독투영와 Meperidine과 저농도 Bupivacaine병합투여의 제통효과 비교 = Comparison of Meperidine and Meperidine Combined with 0.08% Bupivacaine for the pain Relief after Cesarean Section제왕절개술후 통증조절을 위해 경막외 PCA 를 이용한 Meperidine 단독투영와 Meperidine과 저농도 Bupivacaine병합투여의 제통효과 비교

다국어 초록 (Multilingual Abstract)

We performed a study of epidural patient controlled analgesia of meperidine with or without 0.08% bupivacaine for 48 hours after Cesarean section. 51 parturients were ran- domly assigned to one of two treatment groups: 1) epidural 0.2% meperidine group(n: 24) and 2) epidural combined group with 0.2% meperidine and 0.08% bupivacaine(n.27). All parturients used patient controlled analgesia with loading dose, 2 ml/hour continuous infu- sion, 1 ml bolus infusion and lockout time, 8 minutes. Visual analog scales after loading doses were not significantly different in either groups. The total quantity of meperidine consumption and hourly consumption were significantly lower in the combined group than meperidine group(P<0.05). The cumulative amount of meperidine consumption were also significantly lower in the combined group than meperidine group at 6, 12, 24 and 48 hours. In combined group the hourly consumption of meperidine from 3 hours to 12 hours after loading dose was significanly lower than those of meperidine group. Above 90% of parturients were satisfied in both groups. Side effects were numbness(2), nausea(l) and headache(1) in combined group and numbness(2), thigh weakness(1), nausea(1), headache(1) and back pain(2) in epidural meperidine group. There were no case needed specific treat- ment in both groups.
We conclude that analgesic effects were similar in both groups, however the amount of meperidine consumption was less for meperidine group than combined group.