Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP)

다국어 초록 (Multilingual Abstract)

Purpose: To develop a novel combination of controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) with integrated SSFP (CAIPI-iSSFP) for accelerated SSFP imaging without banding artifacts at 3T.
Materials and Methods: CAIPI-iSSFP was developed by adding a dephasing gradient to the balanced SSFP (bSSFP) pulse sequence with a gradient area that results in 2π dephasing across a single pixel. Extended phase graph (EPG) simulations were performed to show the signal behaviors of iSSFP, bSSFP, and RF-spoiled gradient echo (SPGR) sequences. In vivo experiments were performed for brain and abdominal imaging at 3T with simultaneous multi-slice (SMS) acceleration factors of 2, 3 and 4 with CAIPI-iSSFP and CAIPI-bSSFP. The image quality was evaluated by measuring the relative contrast-to-noise ratio (CNR) and by qualitatively assessing banding artifact removal in the brain.
Results: Banding artifacts were removed using CAIPI-iSSFP compared to CAIPI-bSSFP up to an SMS factor of 4 and 3 on brain and liver imaging, respectively. The relative CNRs between gray and white matter were on average 18% lower in CAIPI-iSSFP compared to that of CAIPI-bSSFP.
Conclusion: This study demonstrated that CAIPI-iSSFP provides up to a factor of four acceleration, while minimizing the banding artifacts with up to a 20% decrease in the relative CNR.

참고문헌 (Reference)

• 1 Bilgic B, "Wave-CAIPI for highly accelerated 3D imaging" 73 : 2152-2162, 2015
• 2 Larkman DJ, "Use of multicoil arrays for separation of signal from multiple slices simultaneously excited" 13 : 313-317, 2001
• 3 Haacke EM, "Steadystate free precession imaging in the presence of motion : application for improved visualization of the cerebrospinal fluid" 175 : 545-552, 1990
• 4 Sekihara K, "Steady-state magnetizations in rapid NMR imaging using small flip angles and short repetition intervals" 6 : 157-164, 1987
• 5 Carr H, "Steady-state free precession in nuclear magnetic resonance" 112 : 1693-1701, 1958
• 6 Miller KL, "Steady-state MRI : methods for neuroimaging" 3 : 93-105, 2011
• 7 Zur Y, "Spoiling of transverse magnetization in steady-state sequences" 21 : 251-263, 1991
• 8 Wang Y, "Simultaneous multi-slice Turbo-FLASH imaging with CAIPIRINHA for whole brain distortion-free pseudo-continuous arterial spin labeling at 3 and 7 T" 113 : 279-288, 2015
• 9 Simonetti OP, "Significance of the point of expansion in interpretation of gradient moments and motion sensitivity" 1 : 569-577, 1991
• 10 Pruessmann KP, "SENSE : sensitivity encoding for fast MRI" 42 : 952-962, 1999
• 11 Duerk JL, "Remember true FISP? A high SNR, near 1-second imaging method for T2-like contrast in interventional MRI at .2 T" 8 : 203-208, 1998
• 12 Mikaiel S, "Real-time golden angle radial iSSFP for interventional MRI" 3579-, 2016
• 13 Hargreaves BA, "Rapid gradient-echo imaging" 36 : 1300-1313, 2012
• 14 Gagoski BA, "RARE/turbo spin echo imaging with simultaneous multislice wave-CAIPI" 73 : 929-938, 2015
• 15 Scheffler K, "Principles and applications of balanced SSFP techniques" 13 : 2409-2418, 2003
• 16 Wang Y, "Phase-cycled simultaneous multislice balanced SSFP imaging with CAIPIRINHA for efficient banding reduction" 76 : 1764-1774, 2016
• 17 Wansapura JP, "NMR relaxation times in the human brain at 3.0 tesla" 9 : 531-538, 1999
• 18 Kim MO, "Multislice CAIPIRINHA using view angle tilting technique(CAIPIVAT)" 2 : 43-48, 2016
• 19 Kim D, "Multi-slice imAGe generation using intra-slice paraLLel imaging and Inter-slice shifting(MAGGULLI)" 61 : 1692-1704, 2016
• 20 Axel L, "MR flow imaging by velocitycompensated/uncompensated difference images" 11 : 31-34, 1987
• 21 Sun K, "Integrated SSFP for functional brain mapping at 7T with reduced susceptibility artifact" 276 : 22-30, 2017
• 22 Setsompop K, "Improving diffusion MRI using simultaneous multi-slice echo planar imaging" 63 : 569-580, 2012
• 23 Haacke EM, "Improving MR image quality in the presence of motion by using rephasing gradients" 148 : 1251-1258, 1987
• 24 Scheffler IE, "Helix formation by dAT oligomers. I. Hairpin and straight-chain helices" 36 : 291-304, 1968
• 25 Bieri O, "Fundamentals of balanced steady state free precession MRI" 38 : 2-11, 2013
• 26 Bieri O, "Flow compensation in balanced SSFP sequences" 54 : 901-907, 2005
• 27 Oppelt A, "FISP : a new fast MRI sequence" 54 : 15-18, 1986
• 28 Weigel M, "Extended phase graphs: dephasing, RF pulses, and echoes - pure and simple" 41 : 266-295, 2015
• 29 Crawley AP, "Elimination of transverse coherences in FLASH MRI" 8 : 248-260, 1988
• 30 Breuer FA, "Controlled aliasing in volumetric parallel imaging(2D CAIPIRINHA)" 55 : 549-556, 2006
• 31 Breuer FA, "Controlled aliasing in parallel imaging results in higher acceleration(CAIPIRINHA)for multi-slice imaging" 53 : 684-691, 2005
• 32 Robson PM, "Comprehensive quantification of signal-to-noise ratio and g-factor for image-based and k-space-based parallel imaging reconstructions" 60 : 895-907, 2008
• 33 Stäb D, "CAIPIRINHA accelerated SSFP imaging" 65 : 157-164, 2011
• 34 Setsompop K, "Blipped-controlled aliasing in parallel imaging for simultaneous multislice echo planar imaging with reduced g-factor penalty" 67 : 1210-1224, 2012
• 35 Xiang QS, "Banding artifact removal for bSSFP imaging with an elliptical signal model" 71 : 927-933, 2014
• 36 Shams Z, "Averaged-BOSS: feasibility study and preliminary results" 4216-, 2014
• 37 Khajehim M, "A quantitative analysis of fMRI induced phase changes using averaged-BOSS (A-BOSS)" 3921-, 2015