경계성 절제가능형 췌장 연구 동향에 대한 체계적인 문헌 고찰: 계량서지학적 분석 및 시각화된 분석 = Systematic Review of Research Progress on Borderline Resectable Pancreatic Cancer: A Bibliometric and Visualized Analysis

국문 초록 (Abstract)

췌장암(pancreatic cancer, PC)은 진단과 치료가 가장 어렵고 까다로운 암이다. 그중에서도 경계성 절제가능형 췌장암(borderline resectable pancreatic cancer,BRPC)은 특히 중요한 위치를 차지하는 종양으로 종양을 완전히 제거할 수 있는 절제 가능한 췌장암과 질병이 너무 광범위하게 진행되어 수술이 불가능한 절제 불가능한 췌장암 사이의 중간 단계에 해당한다[1]. 일반적으로 경계성 절제가능형 췌장암(BRPC)은 종양이 주변 혈관을 약간 침범했지만 적절한 수술 전 치료 후 수술로 제거할 가능성이 있는 상태를 말하며 경계성 절제가능형 췌장암 환자(BRPC)의 치료 결과를 개선하기 위해 수술만 아니라 다양한 의학 분야에서 연구가 진행되고 있다[2-5].
서지학(bibliometric analysis)은 특정 연구 분야의 출판물의 성과와 영향력을 양적, 질적 관점에서 조사하는 문헌 분석 방법으로써 주요 연구 동향, 새로운 주제 및 해당 분야의 진화를 파악하는 데 도움이 되며, 과학 분야에 대한 포괄적인 개요를 제공한다[6]. 또한 서지학은 과학 및 학술 커뮤니티에서 정보에 입각한 의사 결정과 전략적 계획을 용이하게 하는 데 도움을 주기 때문에 의학을 포함한 다양한 학문 분야에서 광범위하게 사용되고 있다[7-10]. 그러나 경계성 절제가능형 췌장암에 대한 서지학적 분석은 아직 발표되지 않은 실정이다. 이 연구의 목적은 서지학적 방법을 사용하여 최근 10년간의 경계성 절제가능형 췌장암 연구 동향을 분석하고, 주요 특징을 평가함으로써 해당 연구의 현황과 동향을 더 잘 이해하는 것이다.

다국어 초록 (Multilingual Abstract)

Borderline resectable pancreatic cancer, an intermediate stage between a completely resectable state and an unresectable state, requires a multidisciplinary treatment approach. This study aimed to elucidate the main characteristics and recent research trends regarding borderline resectable pancreatic cancer to gain further insights into them. Data from published papers about borderline resectable pancreatic cancer were collected from Web of Science (2014–2023) for the analysis. This study included 355 papers; data on major countries, publishing organizations, and keywords were collected and analyzed. Furthermore, R studio and VOSviewer were used for the qualitative and quantitative analyses of keywords. Publication of papers on borderline resectable pancreatic cancer was observed to be increasing annually by 12.8%, with the United States and Japan being the main publishing countries. In 2014, keywords related to surgery and chemotherapy were dominant; however, a shift toward more integrative approaches, such as neoadjuvant therapy, was observed over time. This study demonstrates rapidly evolving trends and paradigm changes in the research and management of borderline resectable pancreatic cancer. Thus, the results of this study are expected to contribute to establishing future research strategies and improving patient treatment outcomes.

참고문헌 (Reference)

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