週期的 高蛋白質食餌 給食에 依한 臟器內 酵素活性 變動에 關한 硏究 = A Study on Change of the Enzyme Activity in Rat Organ by Periodic Feeding of High Protein Diet

다국어 초록 (Multilingual Abstract)

This study was planned to observe the effect on change of enzyme activity by periodic feeding of high protein diet on rats maintained with low protein diet. The experimental animals were 136 female albino rats from pure strain, weighing 239-297gm.
The animals were divided into five diet groups: the standard diet group and four of the rice diet supplemented with fish flour groups, once every other day (A group), every two days (B group), every three days (C group) and every four days (D group). The above each group was re-divided into four groups by feeding term of each diet: the terms were 15 days, 30 days, 45 days and 60 days.
The animals were sacrificed after feeding each diet for the corresponding period and glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT) activities in the liver and pancreas, cholinesterase activity and acetylcholin content in the liver and serum were determined.
The results obtained are summarized as follows:
1. The activity of GPT in the respect of experimental diet, tends to decrease in A,B,C and D groups compared with the control group, and in the degree, A group is more remarkable and D group is slighter than any other group. By the feeding terms, 15 days feeding group shows the minimum value and the 60 days feeding group shows the close value to that of the control group.
2. The activity of GOT in the liver is apt to decrease in each diet group and activities in A and B groups are near to the control group, while between D and the control group, some difference is made.
3. The activities of GPT and GOT in the pancreas of each diet group show a tendency to decrease, for those in the control groups, but the difficulty is found to describe the diference in regular tendency among three diet groups. And in feeding term group, GPT activity in the pancreas is similar to a tendency to change of that in the liver i.e, that in the 15 days feeding group is the minimum, and that of the 60 days feeding group is close to that in the control group.
4. The activity of cholinesterase in the liver is higher in all of the supplemented diet group than in the control group, and that in the 15 days feeding group is increased the most remarkable and that in the 30 days feeding group is increased in the minimum degree.
5. The activity of cholinesterase in the serum is found to be increased in all of the supplemented diet group, compared with the control group, as well as in the liver.
6. The contents of acetylcholine in the liver and serum is increased in each diet and feeding term groups, compared with the control group.

목차 (Table of Contents)

• Ⅰ. 緖論
• Ⅱ. 實驗材料 및 方法
• A. 食餌
• B. 實驗 動物
• C. 食餌給與方法과 動物管理
• D. 試料採取
• E. 測定方法
• Ⅲ. 實驗成績
• A. 肝內 GPT와 GOT 活性
• B. 膵內 GPT와 GOT 活性
• C. 肝과 血淸內 cholesterol 活性
• D. 肝과 血淸內 acetylcholine 含有量
• Ⅳ. 總括 및 考察
• Ⅴ. 結論
• 參考文獻