급성편도염에서 편도상피세포의 세균부착에 관한 연구 = Attachment of Bacteria to Tonsillar Epithelial Cell during Acute Tonsillitis

다국어 초록 (Multilingual Abstract)

Adherence of microorganisms to mucosal surface is a general phenomenon among microorganisms infecting the human host. To cause invasive disease, the attached microorganisms must proliferate, form colonies and release extracellular enzymes or toxins which can injure the underlying cells.
The purpose of this study is to investigate the in vivo differences in bacterial attachment between patients with acute tonsillitis and normal control. And we also assess the change of bacterial adherence to epithelial cells of palatine tonsil in vivo according to the age.
This study was carried out on 40 patients suffering from acute tonsillitis and 40 individually matched normal control. None of these subjects had taken antibiotics within two weeks prior to the sampling. After scraping of the surface of tonsil, cellular mixture was counted under the fluorescent microscope. The adherence rate was calculated as number of bacteria attached to each of 50 epithelial cells and we performed conventional bacterial culture simultaneously,
Conclusively, the attachment of bacteria to the tonsillar epithelial cell was significantly greater in the patients with acute tonsillitis than control, and the number of the attached bacteria to the epithelium was decreased with age.