동작 가속도계로 측정한 신체활동수준이 심폐체력과 대사증후군에 미치는 영향에 관한 연구 = Effects of accelerometer-measured daily physical activity on cardiopulmonary fitness and metabolic syndrome in middle-aged women

다국어 초록 (Multilingual Abstract)

Background- Few studies have been conducted to investigate the relationships among daily physical activity, cardiorespiratory fitness (CRF), and metabolic syndrome incidence in Korean middle-aged women.
Methods and Results - A total of 79 apparently healthy women (mean±SD age, 50.1±3.4 years; body mass index, 24.6±2.5kg/m2) was invited to participate in this study. Blood variables including glucose and lipoprotein-lipids were measured in fasting blood samples. Baseline physical activity level was measured with an accelerometer (life corder EX,2006, Suzuken, Japan) for seven consecutive days, and CR fitness was estimated from a sub-maximal cycle ergometer test(828E, Monark, USA). Metabolic syndrome was defined with NCEP ATP-Ⅲ(2001) criteria(except for waist girth; ≥ 80cm in Korean women). Analysis of variance (ANOVA) were used to compare any significant linear trends in mean values of the metabolic syndrome markers across both physical activity and CRF levels. Further, receiver operating curve (ROC) analyses were used to estimate the best-possible cut-off points of daily physical activity and CRF levels for the prevention of the metabolic syndrome in this study population. Cross-tabulations were used to estimate odds-ratios of the metabolic syndrome across the daily physical activity and CRF levels. All statistical significances were tested at p=0.05. The optimal cut-off points of preventing metabolic syndrome appear to be 9,820steps/day and 27.6ml/kg/min for daily physical activity and CRF levels, respectively, in this study population. With respect to daily physical activity, the odds ratios of metabolic syndrome were 1.0 for the active group and 9.1 for the sedentary group, respectively, even after adjusted for age, BMI, body fat, waist, VO2max. With respect to CRF, the odds ratios of metabolic syndrome were 1.0 for the fit group and 0.9 for the unfit group, respectively, even after adjusted for age, BMI, body fat, waist, physical activity. Bivariate correlation analyses showed that daily physical activity(steps/day) level was inversely related to waist, TC/HDL-C, waist/hip ratio, triglyceride, body fat, and it was positively related to HDL-C and VO2max. And CRF was inversely related to waist, DBP, TC/HDL-C and body fat.
Conclusions- Low physical activity is a strong and independent predictor of incident metabolic syndrome in Korean middle-aged women. Consequently. promoting daily physical activities including regular exercise appears to be urgently necessary to prevent the development of the metabolic syndrome along with improved CRF level too.

목차 (Table of Contents)

• 제1장 서론 = 1
• 1. 연구의 필요성 = 1
• 2. 연구의 목적 = 5
• 3. 연구의 가설 = 6
• 4. 연구의 제한점 = 6
• 제2장 이론적 배경 = 7
• 1. 신체활동(Physical activity)의 중요성 = 7
• 2. 신체활동량 측정방법 = 10
• 3. 비만과 대사증후군 = 12
• 4. 신체활동, 심폐체력과 대사증후군과의 관계 = 15
• 제3장 연구 방법 = 18
• 1. 연구 대상 = 18
• 2. 실험 설계 = 19
• 3. 측정 항목 및 분석 방법 = 20
• 1) 신체계측 및 혈압측정, 혈액검사 = 20
• 2) 신체활동 수준 측정 = 20
• 3) 최대산소섭취량(VO2max) 측정 = 22
• 4) 대사증후군의 정의 = 23
• 4. 통계 분석 = 24
• 제4장 연구 결과 = 25
• 1. 대사증후군 여부에 따른 연구대상자의 특성 = 25
• 2-1. 신체활동수준에 따른 대사증후군 지표와 심폐체력비교 = 26
• 2-2. 심폐체력수준에 따른 대사증후군 지표와 신체활동 비교 = 30
• 3. ROC곡선 분석을 통한 대사증후군 판별지표로서의 신체활동량과 심폐체력의 최적 임계점 = 34
• 4-1. ROC곡선의 임계점을 기준으로 나눈 신체활동 상, 하 두집단의 대사증후군과 비만지표의 비교 = 36
• 4-2. ROC곡선의 임계점을 기준으로 나눈 심폐체력 상, 하 두집단의 대사증후군과 비만지표의 비교 = 37
• 5-1. 신체활동수준, 심폐체력과 대사증후군 지표와의 상관관계 = 39
• 5-2. 대사증후군 지표와 비만지표와의 상관관계 = 40
• 5-3. 신체활동수준, 심폐체력과 비만지표와의 상관관계 = 41
• 6-1. 신체활동수준에 따른 대사증후군 유병률과 승산비 비교 = 42
• 6-2. 심폐체력에 따른 대사증후군 유병률과 승산비 비교 = 43
• 제5장 논의 = 45
• 제6장 결론 = 50
• 참고문헌 = 52
• ABSTRACT = 63