40세 이상 한국 성인에서 목둘레와 심혈관 질환 위험인자 및대사증후군과의 관련성: 2019년 국민건강영양조사 = The Relationship between Neck Circumference and Cardiovascular Risk Factors Including Metabolic Syndrome in Korean Adults over 40 Years of Age: The Korean National Health and Nutrition Examination Survey, 2019

국문 초록 (Abstract)

연구배경: 본 연구는 목둘레와 심혈관 질환 위험인자의 관련성을밝히고 한국인에서 대사증후군을 선별하는 데 있어서 적절한 목둘레의 기준점을 제시하고자 한다.
방법: 국민영양조사 제8기 1차년도(2019) 자료를 이용하여, 총 4,208명의 40세 이상 성인을 대상으로 하였다. 목둘레와 심혈관 질환 위험인자 임상지표들과의 상관관계를 확인하기 위하여 상관분석을시행하였다. Receiver operating characteristic curve 분석을 시행하여대사증후군을 선별하는 적절한 목둘레의 기준점을 제시하였고, 이를 바탕으로 로지스틱 회귀분석을 시행하였다.
결과: 목둘레는 남성과 여성 모두에서 허리둘레, BMI, 이완기 혈압,공복 혈당, 공복 인슐린, 당화혈색소, 중성지방과 양의 상관관계를보였다. 목둘레는 남성에서 비-고밀도 콜레스테롤, 여성에서 수축기혈압과 양의 상관관계를 보였으며, 남성과 여성에서 고밀도 콜레스테롤과 음의 상관관계를 보였다. 대사증후군을 선별하는 목둘레 기준점은 남성 38.0 cm, 여성 33.0 cm이 적절하며, 이를 기준으로 하여목둘레가 긴 그룹은 짧은 그룹에 비해 남성과 여성 모두에서 고혈압(남성 1.780, 95% confidence interval [CI] 1.352–2.344; 여성 1.690,95% CI 1.330–2.147), 당뇨병(남성 1.470, 95% CI 1.068–2.021; 여성2.078, 95% CI 1.522–2.836), 이상지질혈증(남성 1.888, 95% CI 1.432–2.490; 여성 1.712, 95% CI 1.345–2.180), 대사증후군(남성 2.390, 95%CI 1.888–3.026; 여성 2.919, 95% CI 2.269–3.757)의 교차비가 유의하게 증가하였다.
결론: 목둘레는 한국인에서 심혈관 질환 위험인자들과 관련이 있으며 대사증후군을 예측하는 데 사용할 수 있는 지표이다.

다국어 초록 (Multilingual Abstract)

Background: We aimed to evaluate the correlation between neck circumference (NC) and cardiovascular risk factors and to propose an optimal cut-offvalue of NC for the screening of metabolic syndrome in the Korean population.
Methods: From the database of the Korean National Health and Nutrition Examination Survey 2019, we extracted the data of 4,208 participants withavailable relevant clinical information. Correlation analyses were performed to evaluate the association between NC and cardiovascular risk factors.
Receiver operating characteristics curve analysis was used to obtain a cut-off value of NC for the screening of metabolic syndrome.
Results: NC showed a positive correlation with waist circumference, body mass index, diastolic blood pressure, fasting blood sugar, fasting insulin,HbA1c, and triglyceride levels in both male and female. It showed a positive correlation with non-HDL cholesterol in men, systolic blood pressure inwomen, and a negative correlation with HDL cholesterol in both sexes. The optimal cut-off value for screening metabolic syndrome was 38.0 cm inmen and 33.0 cm in women. The odds ratio of the “longer NC” group was significantly higher for hypertension (male 1.780, 95% CI 1.352–2.344;female 1.690, 95% CI 1.330–2.147), diabetes (male 1.470, 95% CI 1.068–2.021; female 2.078, 95% CI 1.552–2.836), dyslipidemia (male 1.888, 95% CI1.432–2.490; female 1.712, 95% CI 1.345–2.180), and metabolic syndrome (male 2.390, 95% CI 1.888–3.026; female 2.919, 95% CI 2.269–3.757).
Conclusion: NC correlated with cardiovascular risk factors and can be used to predict metabolic syndrome in the Korean population.

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