Brucella病에 關한 硏究 : 姙娠海??에 대한 Br, 1119-3 菌株 및 178菌株의 血淸抗體價의 消長에 對하여 (其一) The fructuation of agglutination titer on pregnant Guinea-pig's by inoculation of Strain 1119-3 and 178 = Studies on the Brucellosis

국문 초록 (Abstract)

금반임신해명에 對하여 Br, 1119-3 菌株 및 Br, 178 菌株를 各各 接種하여 血淸抗體價의 消長을 標準試驗管法에 依하여 觀察한 바 Br, 178 菌株는 Br, 1119-3 菌株보다 若干 높은 强陽性力價를 나타내고 Br, 1119-3 菌株를 接種時는 短時日에 急速한 力價의 下降을 나타냈으며 또한 力價下降時 卽 1:50倍 不完全 및 完全凝集力價時에 해명웅을 混合飼育하였던 바 力價上昇은 없었고 菌證明도 되지 않았다. Br,178 菌株는 大體로 높은 血淸抗體價를 繼續維持하였고 力價下降時 卽 100倍不完全 및 完全凝集價時에 해명웅을 混合飼育하였던 바 强陽性力價로 다시 上昇하였으며 이는 해명웅의 同居刺戟에 依한 自體性홀몬 分泌가 血淸凝集反應에 影響을 준 것이 아닌가 思料되었고, 살처분해명에서 菌分離證明이 되었으나 體內에 胎兒는 없었다. 그리고 처음 流産은 Br,1119-3 菌株 및 Br, 178菌株 共히 接種後 8∼35日 사이에 일어났다.

다국어 초록 (Multilingual Abstract)

Pregnant guinea pigs were inoculated with strain 1119-3 and 178, and their agglutination titers were observed by standard tube method.
The results obtained are as follows:
The guinea pigs which were injected with strain 1119-3 showedhigh reac or titers but it was slightly lower than those of strain 178 and decreased promptly. When their titers were dropped at 1:50 incomplete or comple'e, they were reared with a male in the same cage but their agglutination titers were unchanged. At autopsy, the strain was not detected.
In the case of strain 178, they maintained relatively high reactor titer. When they showed at titer of 1:100 incompleteor completo, they rose again at a level of high reactor titer by adding of male animal. It gives us a presumption that there is a certain relations between the secretion of ordinary sexual hormones and serum agglutination. The strain was manifested by autopsy but any fetus was not detected in this case.
It seem in both groups that abortions had taken place between eight and 35 days after inoculation.

목차 (Table of Contents)

• Ⅰ. 緖 論
• Ⅱ. 試驗材料 및 方法
• Ⅲ. 結果 및 考察
• Ⅳ. 摘 要
• Ⅴ. 引用文獻
• Ⅵ. Summary