신경섬유종증 1형에서 발생한 파열된 상직장동맥류의 경도관 동맥 색전술: 증례 보고 = Transcatheter Arterial Embolization of a Ruptured Superior Rectal Artery Aneurysm in Type 1 Neurofibromatosis: A Case Report

다국어 초록 (Multilingual Abstract)

Neurofibromatosis type 1 (NF1) is a common autosomal-dominant disorder. Vasculopathies associated with NF1 are rare and can cause aneurysms, stenoses, and arteriovenous malformations.
Aneurysms may rupture spontaneously, which could be fatal. Spontaneous mesenteric hemorrhage due to rupture of an inferior mesenteric artery aneurysm associated with NF1 has rarely been reported. Herein, we report a case of spontaneous rupture of a fusiform aneurysm in the superior rectal artery in a 56-year-old woman with NF1 who was successfully treated with transcatheter arterial embolization.

국문 초록 (Abstract)

신경섬유종증 1형은 상염색체우성질환으로 가장 흔한 유전 질환 중 하나이다. 혈관병증은 드물게 발생할 수 있으며, 신경섬유종증 1형 혈관병증은 동맥류, 협착, 동정맥기형의 형태로 나타난다. 동맥류의 경우 자연파열과 같은 치명적인 합병증을 유발할 수 있다. 신경섬유종증 1 형과 연관된 하장간막동맥류의 파열로 인한 장간막출혈은 매우 드물게 보고되고 있다. 이에저자들은 신경섬유종증 1형에 의한 방추형 상직장동맥류의 자발적 파열로 내원한 56세 여성환자에서 코일을 이용한 경도관 동맥 색전술을 시행하여 성공적으로 치료한 1예를 경험하였기에 이를 보고하고자 한다.

참고문헌 (Reference)

• 1 Oderich GS, "Vascular abnormalities in patients with neurofibromatosis syndrome type I : clinical spectrum, management, and results" 46 : 475-484, 2007
• 2 Kok HK, "Systematic review and single-center experience for endovascular management of visceral and renal artery aneurysms" 27 : 1630-1641, 2016
• 3 Yow KH, "Successful combined management for ruptured superior rectal artery aneurysm in neurofibromatosis type 1" 29 : 1317.e13-1317.e16, 2015
• 4 Makino K, "Spontaneous rupture of a dissecting aneurysm in the superior rectal artery of a patient with neurofibromatosis type 1 : a case report" 7 : 249-, 2013
• 5 Kerger L, "Ruptured inferior mesenteric artery aneurysm in a patient with a type 1 neurofibromatosis" 26 : 858.e1-858.e2, 2012
• 6 Delis KT, "Neurofibromatosis type 1 : from presentation and diagnosis to vascular and endovascular therapy" 18 : 226-237, 2006
• 7 Patel NB, "Musculoskeletal manifestations of neurofibromatosis type 1" 199 : W99-W106, 2012
• 8 Sacar M, "Inferior mesenteric artery aneurysm combined with renal artery stenosis in a patient with neurofibromatosis" 18 : 217-220, 2006
• 9 Levy AD, "From the archives of the AFIP : abdominal neoplasms in patients with neurofibromatosis type 1 : radiologic-pathologic correlation" 25 : 455-480, 2005
• 10 Loffroy R, "Endovascular management of visceral artery aneurysms : when to watch, when to intervene" 7 : 143-148, 2015