한국 성인에서 Relative Fat Mass 공식의 적용 = Application of Relative Fat Mass Equation in Korean Adults

다국어 초록 (Multilingual Abstract)

Background: Body mass index (BMI) has limitations in determining body fat percentage and body fat distribution, and causes misclassification of bodyfat-defined obesity. As high body fat percentage is associated with mortality, an accurate assessment of body fat percentage is considered clinicallyimportant. Recently, Woolcott and Bergman reported a relative fat mass (RFM) equation which calculated the body fat percentage using the heightand waist circumferences. However, as RFM has been studied only in European-, Mexican-, and African-Americans, an assessment in Asians wasneeded. Therefore, we aimed to evaluate the applicability of RFM in Korean adults.
Methods: This study included 7,733 adults who visited a Sanggye Paik Hospital Health Promotion Center from May 1, 2016 to November 12, 2018. BMIand RFM were calculated by measuring height, weight, and waist circumference. The total body fat (TBF) percentage was measured by bioelectricalimpedance analysis. We compared the BMI, RFM, and TBF percentage to assess the applicability of RFM in Korean adults.
Results: RFM had a statistically significant correlation with TBF percentage in both male and female (male: β=0.808, R2=0.653, female: β=0.766,R2=0.587, P<0.001). In the Bland-Altman plot, RFM showed good agreement with the TBF percentage within the 95% confidence interval.
Conclusion: The RFM equation can be used to predict TBF percentage in Korean adults.

국문 초록 (Abstract)

연구배경: 체질량지수(body mass index, BMI)는 체지방률 및 체지방분포를 확인하는데 한계가 있으며, 체지방률로 정의하는 비만의 분류 오류를 일으킨다. 높은 체지방률은 여러 질환 및 사망과 관련이있기 때문에 체지방률을 정확히 평가하는 것은 임상적으로 중요하게 여겨진다. 최근 미국의 Woolcott과 Bergman은 키와 허리둘레로체지방률을 계산하는 relative fat mass (RFM) 공식을 발표하였다. 그러나 RFM은 유럽계, 멕시코계, 아프리카계 미국인을 대상으로 연구되어 아시아인에 대한 평가가 필요하다. 따라서 본 연구는 한국 성인에서 RFM 적용 가능성에 대해 알아보고자 한다.
방법: 2016년 5월부터 2018년 11월 12일까지 건강증진센터에 내원한7,733명의 성인을 대상으로 하였고 키, 체중, 허리둘레를 측정하여BMI, RFM을 계산한 뒤 bioelectrical impedance analysis (BIA)로 측정한 체지방률과 비교하여 한국인에서 RFM 적용 가능성을 평가하였다.
결과: 남녀 모두에서 RFM은 total body fat (TBF) percentage와 통계적으로 유의한 상관관계를 가졌다(남: β=0.808, R2=0.653, 여: β=0.766,R2=0.587, P<0.001). Bland-Altman plot에서 RFM은 TBF percentage와95% limits of agreement 내에서 좋은 일치도를 보였다.
결론: 한국 성인에서 RFM 공식은 TBF percentage를 예측하는 도구로써 이용될 수 있다.

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