白鼠背部 實驗創傷內 亞鉛濃度 比較測定 = Measurement of Zinc Concentrations in the Experimental Wouds of the White Rats

다국어 초록 (Multilingual Abstract)

The purpose of this experimental tstudy was to measure zinc concentrations in the experimental wounds of the white rats which had received oral supplementation of zinc sulfate 4.4mg(equivalent to 1mg of elemental zinc) or zinc sulfate 4.4mg plus ascorbic acid 8mg daily.
Twenty seven white rats were divided into three groups;
control group, ad. zinc group, ad. zinc plus ascorbic acid group. . Three artificial wounds were made on the back surface of each animal and tissue biopsies were taken from the healing wounds 1st week, 2nd week, 3rd week postoperatively, and then all samples were analyzed for zinc concentration using atomic absorption spectrophotometer.
The results were summarized as follows;
Initial sharp decrease of zinc concentration was observed in all animal groups during the 1st experimental week.
The concentration increased gradually during the 2nd and 3rd experimental week, but the final concentration didn't regain th original one.
Zinc suplementation resulted in significant increase of zinc level compared with control group on 2nd and 3rd postoperative week. (P<0.05)
Local zinc concention was not influenced by oral supplemention of ascorbic acid.