Clinicopathologic study of nevus and tumor on acral area and its association with location = Clinicopathologic study of nevus and tumor on acral area and its association with location

다국어 초록 (Multilingual Abstract)

Background: A variety of benign and malignant nevus and tumors can occur in the acral area. Clinicopathologic studies of nevus and tumor on the acral area are still lacking. Objectives: To find the location on the acral area where nevus frequently occurred and to determine the need for screening by finding the ratio between benign and malignant tumors. Methods: We retrospectively reviewed the medical records, clinical photos, and histologic slides of 144 patients with nevus and tumor on acral area during 8 years. We investigated the clicopathologic information from patient’s follow up data including age, sex, location of lesion, histopathologic finding. Results: Most frequently the lesions appeared in the 2nd and 3rd fingers (33/78) and both the great toes of the foot (25/49) and more frequently on the right foot (10/16). Occurrences in females were twice as much (1:1.8) compared to males while age was a nonfactor. Histopathologic reviews have showed over half the nevus with aytpia (20/45) and 12/89 tumors to be malignant Conclusion: Among the patients whom lesions appeared on the right 85-90% were right-handed and right-footed. The frequent use and weight bearing of the dominant side seemed to cause trauma leading to the appearance of lesions. Melanoma in the acral areas occurred much more in Korean giving further evidence to its association with trauma. Half of the nevus showed atypia, therefore nevus on the acral area would require biopsy in a all cases and need frequent re-screeing.