지구력 및 스프린트 훈련이 흰쥐 후지근의 Myosin Hevey Chain 변화에 미치는 영향 = Effect of Endurance and Sprint training on the Change of Myosin Heavy chain in the Hindlimb Muscles of Rat

다국어 초록 (Multilingual Abstract)

The purpose of this study was to evaluate of sprint and endurance training for 8 week on transformational change of the skeletal myosin heavy chain(MHC) isoforms at transcriptional and translational levels in the hindlimb musculature of Sprague-Dawley rats. All animals were divided into non-exercise control group endurance exercise group, and sprint exercise group. In 2 exercise groups animals received sprint or endurance treadmill training for 8 week. The results of this study were followed as:
1. After endurance or sprint exercise for 8 weeks there was significant reduction of body weight but significant increase of muscle weight in all the three muscles weight, which meant these exercises induced muscular hypertrophy.
2. Comparing control group, endurance exercise group showed significant increase in type Ⅰ MHC protein and significant decrease in type Ⅱa MHC protein of the soleus muscle on the myosin ATPase enzyme histochemistry study. However, sprint exercise produce to reverse proportional changes of these 2 MHC isoproteins observed in endurance exercise group.
3. In the MGC, endurance exercise group resulted in significant increase for proportion of type Ⅰ, Ⅱa MHC isoproteins and significant decrease of that of type Ⅱb. In addition sprint exercise caused to increase in Ⅱx MHC isoprotein but decrease in type Ⅱb.
4. On the myosin ATPase enzyme histochemistry study. there was noted significant increase of percent ratio of type Ⅰ, Ⅱa, Ⅱx in endurance exercise group and that of type Ⅱx in sprint exercise of the tibialis anterior Only decrement of type Ⅱb MHC isoprotein proportion was measured in both sprint exercise and endurance exercise.
From above results it could suggest that different type of exercise induce change of myosin heavy chain protein in the hindlimb musculature of rats.

목차 (Table of Contents)

• ■목차■
• Ⅰ. 서론
• Ⅱ. 연구 방법
• 1. 실험대상
• 2. 훈련계획
• 3. 골격근의 적출
• 4. Myosin Atpase 염색방법 및 분석
• 5. 통계처리
• Ⅲ. 결과
• 1. 체중 및 근중량의 변화
• 2. 훈련 형태에 따른 근 섬유 조성의 변화
• Ⅳ. 논의
• Ⅴ. 결론
• 참고문헌