Beta resorcylic acid lactones (RALs) from fungi: chemistry, biology, and biosynthesis

다국어 초록 (Multilingual Abstract)

β-Resorcylic acid lactones (RALs) are one ofthe major polyketides produced by fungi, and some of themhave a diverse array of biological activities. Most RALs featurea 14-membered macrocyclic ring fused to β-resorcylicacid (2,4-dihydroxybenzoic acid). In this review, more than100 RAL-type of compounds are structurally classified intothree groups; 14-membered RALs with 17R configuration,14-membered RALs with 17S configuration, and benzopyranones/benzofuranones, and they are reviewed comprehensivelyin terms of chemistry, biological activities, andbiosynthetic pathways.

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