Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones

다국어 초록 (Multilingual Abstract)

Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medicalcomplications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac andbrain function, and other health benefits, in addition to weight loss. However, concerns have also been raised on side effects including muscle loss, ketosis, and electrolyte imbalance. Of particular concern, the effect of intermittent fasting on hormonal circadianrhythms has received little attention. Given the known importance of circadian hormonal changes to normal physiology, potentialdetrimental effects by dysregulation of hormonal changes deserve careful discussions. In this review, we describe the changes in circadian rhythms of hormones caused by intermittent fasting. We covered major hormones commonly pathophysiologically involvedin clinical endocrinology, including insulin, thyroid hormones, and glucocorticoids. Given that intermittent fasting could alter boththe level and frequency of hormone secretion, decisions on practicing intermittent fasting should take more considerations on potential detrimental consequences versus beneficial effects pertaining to individual health conditions.

참고문헌 (Reference)

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