전산화단층촬영 환자에서 조영제 사용에 따른 부작용의 역학적 특성
저자
발행사항
대전 : 충남대학교 보건ㆍ바이오산업기술대학원, 2007
학위논문사항
학위(석사)-- 충남대학교 보건ㆍ바이오산업기술 대학원 : 보건학과 보건학전공 2007. 2
발행연도
2007
작성언어
한국어
DDC
614 판사항(20)
발행국(도시)
대전
기타서명
Epidemiologic Characteristics of Side Effects from the Use of Contrast Media in the Experienced CT examination
형태사항
44 p. : 삽화 ; 26 cm.
일반주기명
지도교수:이태용
참고문헌 : p.39-41
소장기관
This research was conducted in diagnostic radiology clinic of a university hospital, from Jan 1, 2004 to July 31, 2006. It was done as follow. First, CT examination was conducted to 39,426 patients and then the intravenous injection of contrast media was done to 25,089 patients of them. In the end, the children under ten years of age and critical patients were excluded from those who were tested, and 252 patients who complained side effects of contrast media among 23,868 patients were analyzed for the incidence, symptoms and risk factors of side effects of contrast media.
1. Looking into the incidence of side effects of contrast media, there were side effects in 252 patients(1.1%) of 23,868 patients who were taken examination, and in gender, it was higher in females than males, as they happened in 127(1.2%) of 10,550 females and 125(0.9%) of 13,318 males, in age, it was relatively high in the people under 50 years of age, and, as they got older, the incidence of side effects got more decreased. In the incidence according to the state of patients, there were more side effects in outpatients than inpatients, as they happened in 188(1.2%) of 16,016 outpatients and in 64(0.8%) of 7,852 inpatients.
2. In the disease of survey subjects, there were more side effects in the patients who had a case history than in the patients whose case history was not known and exactly grasped, as they happened in 213(1.2%) of 17,788 patients of the former and in 39(0.6%) of 6,080 patients of the latter.
3. Looking into the symptoms of the side effects of contrast media, there were total 338 cases of symptom factors in 252 patients who had them, such as 227 cases(67.2%) in a dermatological system, 66 cases(19.5%) in a digestive system, 28 cases(8.3%) in a respiratory system, 14 cases(4.1%) in a nervous system, and 3 cases(0.9%) in a circulatory system. And in the frequency by symptoms of side-effects, there were 124 cases(36.7%) in urticaria, which was highest, and 73 cases(21.6%) in pruritus, followed by in the order of symptoms of vomiting, and edema of the injected region or facial region. In the distribution of occurrence by symptoms, there were 177 patients(70.2%) who had one symptom, which was highest, 65 patients(25.8%) who had two symptoms, 8 patients(3.2%) who had 3 symptoms, and 2 patients(0.8%) who had four symptoms .
4. As a result of Multilogistics Regression Analysis, the incidence of side effects of contrast media was high in the patients who had hypertension, kidney disease, diabetics, allergy, asthma, respiratory ailments, and malignant neoplasm, and there was significance in the patients who had diseases in the circulatory system, nervous system, and other unspecified diseases which were not insignificant in the Univariate analysis. There was no significant incidence of side effects in the patients of hematosis, lymph, the spleen, endocrine, sense, dermatology, and musculoskeleton.
In conclusion, in this research, risk factors related with the occurrence of side effects of contrast media could be grasped, and with the development of CT equipment and improvement in the appreciation of health, CT examination is getting increased every year, and so the use of contrast media will increase. Therefore, as it is expected that the frequency of occurrence of side effects will also increase, it is considered that it is necessary to explore the devices to minimize the incidence of side effects by continuously grasping risk factors of the causes of the occurrence of side effects and collecting information about patients.
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